Description

2-Propen-1-One, 2-Fluoro-1-(5-Nitro-2-Pyridinyl)- (9Ci) is a specialized fluorinated pyridine derivative, serving as a high-value building block in advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluoro substituent, makes it a critical intermediate for constructing complex molecules with targeted electronic and steric properties. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its fluorinated nitro-pyridine scaffold.
• Material Science Research: Acts as a precursor for functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags and molecular probes for biochemical assays.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Academic & Contract Research: A valuable reagent for universities and CROs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Propen-1-One, 2-Fluoro-1-(5-Nitro-2-Pyridinyl)- (9Ci)
CAS No.	506437-49-6
Molecular Formula	C8H5FN2O3
Molecular Weight	196.14 g/mol
Synonyms	2-Fluoro-1-(5-nitropyridin-2-yl)prop-2-en-1-one; 2-Fluoro-1-(5-nitro-2-pyridinyl)-2-propen-1-one; 1-(5-Nitro-2-pyridinyl)-2-fluoro-2-propen-1-one; 2-Fluoro-1-(5-nitro-2-pyridinyl)ethenone; (2-Fluoroacryloyl)(5-nitropyridin-2-yl)methanone; 5-Nitro-2-(2-fluoroacryloyl)pyridine; 2-Pyridinecarbonyl fluoride, 5-nitro- derivative
EINECS	Contact for details

Quality Control

Our 2-Propen-1-One, 2-Fluoro-1-(5-Nitro-2-Pyridinyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.