Description

(2S,3R)-1(2H)-Pyridinecarboxylic Acid, 3,6-Dihydro-3-Hydroxy-2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a critical building block for complex molecule construction. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex target molecules.
• Asymmetric Synthesis: Utilized as a building block in stereoselective chemical reactions to introduce specific chiral centers.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of specialty chemicals and advanced materials.
• Academic & Industrial Research: Used in methodological studies and process chemistry development within R&D laboratories.
• Ligand and Catalyst Development: Potential use in the synthesis of novel chiral ligands or organocatalysts for catalytic applications.

Basic Information

Product Name	(2S,3R)-1(2H)-Pyridinecarboxylic Acid, 3,6-Dihydro-3-Hydroxy-2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester
CAS No.	505085-66-5
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	tert-Butyl (2S,3R)-3,6-dihydro-3-hydroxy-2-(hydroxymethyl)-1(2H)-pyridinecarboxylate; (2S,3R)-3,6-Dihydro-3-hydroxy-2-(hydroxymethyl)-1(2H)-pyridinecarboxylic Acid 1,1-Dimethylethyl Ester; (2S,3R)-3-Hydroxy-2-(hydroxymethyl)-1,2,3,6-tetrahydropyridine-1-carboxylic Acid tert-Butyl Ester; (2S,3R)-N-Boc-3-hydroxy-2-(hydroxymethyl)-1,2,3,6-tetrahydropyridine; Chiral Dihydroxypyridine Derivative; Boc-Protected Dihydroxypyridine Intermediate
EINECS	Contact for details

Quality Control

Our production of (2S,3R)-1(2H)-Pyridinecarboxylic Acid, 3,6-Dihydro-3-Hydroxy-2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chiral purity. All materials are characterized by advanced analytical techniques including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.