Description

4-Methyl-6-Chloronicotinic Acid is a high-purity, versatile chloronicotinic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated pyridine structure, which is essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging its chloronicotinate core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis.
• Material Science Research: Employed in the development of functional organic materials and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific halogenated pyridine motifs.

Basic Information

Product Name	4-Methyl-6-Chloronicotinic Acid
CAS No.	503555-50-8
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	6-Chloro-4-methylnicotinic acid; 4-Methyl-6-chloropyridine-3-carboxylic acid; 3-Carboxy-6-chloro-4-methylpyridine; 6-Chloro-4-picolinic acid; 4-Methyl-6-chloro-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-6-Chloronicotinic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.