Description

tert-Butyl 5-Bromo-2-Chlorobenzoate is a high-purity, versatile benzoate ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of halogen substituents, which enable selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Used in university and institutional labs for methodological studies in halogenation, esterification, and palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	tert-Butyl 5-Bromo-2-Chlorobenzoate
CAS No.	503555-23-5
Molecular Formula	C11H12BrClO2
Molecular Weight	291.57 g/mol
Synonyms	5-Bromo-2-chlorobenzoic acid tert-butyl ester; 2-Chloro-5-bromobenzoic acid tert-butyl ester; tert-Butyl 5-bromo-2-chlorobenzoate; Benzoic acid, 5-bromo-2-chloro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 5-bromo-2-chlorobenzoate; 2-Chloro-5-bromobenzoic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 5-Bromo-2-Chlorobenzoate is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to high-purity intermediates supports your R&D and scale-up processes with the traceability and documentation required in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.