Description

5-o-Benzoyl-1,2,3-Tri-o-Acetyl-4-C-Methyl-D-Ribofuranose is a key protected ribofuranose derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile, stereochemically defined scaffold for constructing complex nucleoside analogs and other bioactive molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of antiviral and anticancer therapeutics.

Application

• Nucleoside Analog Synthesis: A vital precursor for the synthesis of modified nucleosides with potential antiviral or anticancer activity.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting viral polymerases.
• Carbohydrate Chemistry: Serves as a protected sugar donor in glycosylation reactions for constructing complex oligosaccharides or glycoconjugates.
• Biochemical Research: Employed in the study of enzyme mechanisms and as a substrate analog for nucleoside-processing enzymes.
• Prodrug Development: Utilized in designing prodrugs of nucleoside-based therapeutics to improve bioavailability and targeting.
• Labeled Compound Synthesis: Acts as a starting material for the synthesis of isotopically labeled (e.g., 13C, 2H) compounds for metabolic and pharmacokinetic studies.

Basic Information

Product Name	5-o-Benzoyl-1,2,3-Tri-o-Acetyl-4-C-Methyl-D-Ribofuranose
CAS No.	503543-44-0
Molecular Formula	C19H22O9
Molecular Weight	394.37 g/mol
Synonyms	4-C-Methyl-1,2,3-tri-O-acetyl-5-O-benzoyl-D-ribofuranose; 1,2,3-Tri-O-acetyl-5-O-benzoyl-4-C-methyl-D-ribofuranose; 4-C-Methyl-D-ribofuranose, 1,2,3-triacetate 5-benzoate; 5-O-Benzoyl-1,2,3-tri-O-acetyl-4-C-methyl-D-ribofuranose; Protected 4-C-Methylribofuranose; Benzoyl Acetyl Methyl Ribofuranose Derivative
EINECS	Contact for details

Quality Control

Our 5-o-Benzoyl-1,2,3-Tri-o-Acetyl-4-C-Methyl-D-Ribofuranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and GMP-grade synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines for stability and impurity characterization to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.