Description

4-(6-Amino-3-Pyridinyl)Benzonitrile is a high-purity, bifunctional aromatic nitrile building block featuring both an amino and a cyano group on a biphenyl-like scaffold. This compound is of significant value in advanced organic synthesis, enabling the construction of complex molecular architectures for pharmaceutical and materials research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and as a precursor for functional polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products.
• Ligand Synthesis: Serves as a precursor for constructing chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing high-performance polymers with specific thermal or mechanical properties.
• Material Science: Employed in the research and development of organic electronic materials, such as semiconductors for OLEDs.
• Chemical Biology: Useful as a probe or linker in bioconjugation and the development of chemical tools.

Basic Information

Product Name	4-(6-Amino-3-Pyridinyl)Benzonitrile
CAS No.	503536-78-5
Molecular Formula	C12H9N3
Molecular Weight	195.22 g/mol
Synonyms	4-(6-Aminopyridin-3-yl)benzonitrile; 3'-Amino-4-cyanobiphenyl-3-carbonitrile; 5-(4-Cyanophenyl)pyridin-2-amine; 2-Amino-5-(4-cyanophenyl)pyridine; [1,1'-Biphenyl]-3-carbonitrile, 3'-amino-4'-cyano-; 4-(2-Aminopyridin-5-yl)benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-(6-Amino-3-Pyridinyl)Benzonitrile is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.