Description

Benzoic Acid, 3-(1-Aminocyclopropyl)-, 1,1-Dimethylethyl Ester is a high-purity, specialized organic compound featuring a unique cyclopropylamine-substituted benzoate structure. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in sophisticated organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Proteolysis-Targeting Chimeras (PROTACs): Used in the research and development of targeted protein degradation therapeutics due to its functionalized amine and ester groups.
• Agrochemical Synthesis: Intermediate for creating advanced crop protection agents and pesticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and functional organic materials.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the design of bioactive molecular probes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Benzoic Acid, 3-(1-Aminocyclopropyl)-, 1,1-Dimethylethyl Ester
CAS No.	503417-35-4
Molecular Formula	C15H21NO2
Molecular Weight	247.33 g/mol
Synonyms	tert-Butyl 3-(1-aminocyclopropyl)benzoate; 3-(1-Aminocyclopropyl)benzoic acid tert-butyl ester; 1,1-Dimethylethyl 3-(1-aminocyclopropyl)benzoate; 3-(1-Aminocyclopropyl)-benzoic acid 1,1-dimethylethyl ester; Benzoic acid, 3-(1-aminocyclopropyl)-, tert-butyl ester; tert-Butyl 3-(aminocyclopropyl)benzoate; (3-(tert-Butoxycarbonyl)phenyl)cyclopropylamine
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-(1-Aminocyclopropyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each shipment. We support development and commercial projects requiring material that meets ICH Q7 guidelines and other relevant quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.