Description

2-Methoxy-4-Methyl-Pyridine-5-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing functionalized pyridine scaffolds.
• Agrochemical Synthesis: Used to construct novel active ingredients for crop protection products through palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic pathways.

Basic Information

Product Name	2-Methoxy-4-Methyl-Pyridine-5-Boronic Acid
CAS No.	503184-35-8
Molecular Formula	C8H12BNO3
Molecular Weight	181.00 g/mol
Synonyms	(2-Methoxy-4-methylpyridin-5-yl)boronic acid; 5-Borono-2-methoxy-4-methylpyridine; 4-Methyl-2-methoxypyridine-5-boronic acid; 2-Methoxy-4-methyl-5-pyridineboronic acid; 2-Methoxy-4-methylpyridine-5-boronic acid pinacol ester (common protected form); 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxy-4-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-4-Methyl-Pyridine-5-Boronic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. A Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.