Description

2H-Pyran-3-Carboxylicacid,4-Aminotetrahydro-,Methylester,(3R,4R)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters because its unique fused pyran ring structure and functional groups make it a versatile intermediate for constructing complex molecules with precise three-dimensional architecture. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients. The product is supplied under strict quality control to ensure batch-to-batch consistency for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and metabolic diseases.
• Asymmetric Catalysis & Synthesis: Used as a precursor or ligand in catalytic systems to induce chirality in synthetic pathways, enabling the production of enantiomerically pure compounds.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to explore novel chemical space and optimize the biological activity of lead compounds.
• Agrochemical Research: Acts as a building block for the synthesis of novel herbicides, fungicides, or insecticides that require specific stereochemistry for efficacy.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development in organic chemistry and the synthesis of complex natural product analogs.
• Process Chemistry Development: Investigated for scalable synthetic routes in pilot plants, focusing on yield optimization and impurity profile control for future commercial manufacturing.

Basic Information

Product Name	2H-Pyran-3-Carboxylicacid,4-Aminotetrahydro-,Methylester,(3R,4R)-(9Ci)
CAS No.	503168-22-7
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(3R,4R)-4-Aminotetrahydro-2H-pyran-3-carboxylic acid methyl ester; Methyl (3R,4R)-4-aminotetrahydro-2H-pyran-3-carboxylate; 4-Aminotetrahydro-2H-pyran-3-carboxylic Acid Methyl Ester, (3R,4R)-; (3R,4R)-Methyl 4-aminotetrahydro-2H-pyran-3-carboxylate; 503168-22-7; (3R,4R)-4-Amino-tetrahydro-pyran-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2H-Pyran-3-Carboxylicacid,4-Aminotetrahydro-,Methylester,(3R,4R)-(9Ci) is characterized and released based on a comprehensive specification, including chiral purity and chemical identity verification. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (3R,4R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.