Description

4-Chloro-2-Chloromethyl-3-Methoxypyridine, HCl is a high-purity, versatile pyridine derivative building block essential for advanced organic synthesis. Its bifunctional chlorinated structure makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactive chloromethyl and chloro substituents.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	4-Chloro-2-Chloromethyl-3-Methoxypyridine, HCl
CAS No.	503058-51-3
Molecular Formula	C7H7Cl2NO • HCl
Molecular Weight	228.50 g/mol (Free base: 192.05 g/mol)
Synonyms	4-Chloro-2-(chloromethyl)-3-methoxypyridine Hydrochloride; 3-Methoxy-4-chloro-2-chloromethylpyridine HCl; 2-(Chloromethyl)-4-chloro-3-methoxypyridine Hydrochloride; 503058-51-3; 4-Chloro-2-chloromethyl-3-methoxypyridine Hydrochloride Salt
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Chloromethyl-3-Methoxypyridine, HCl is produced under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure compliance with industry standards for fine chemical intermediates. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.