Description

tert-Butyl 2-Aminoadamantane-2-Carboxylate is a high-purity, functionalized adamantane derivative that serves as a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry where its rigid, lipophilic adamantane core and protected amine/carboxylate groups offer unique structural and pharmacokinetic properties. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including protease inhibitors and other bioactive compounds targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting viral proteases and neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to introduce the rigid, three-dimensional adamantane scaffold into lead compounds.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of potent protease inhibitors.
• Advanced Organic Synthesis: Employed as a versatile intermediate for further functionalization, leveraging both the tert-butyl ester and primary amine groups.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or dendrimers with unique thermal and mechanical properties.

Basic Information

Product Name	tert-Butyl 2-Aminoadamantane-2-Carboxylate
CAS No.	502937-07-7
Molecular Formula	C15H25NO2
Molecular Weight	251.37 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)adamantane-2-carboxylic acid; 2-Amino-2-adamantanecarboxylic acid tert-butyl ester; tert-Butyl 2-amino-2-adamantanecarboxylate; 2-Boc-amino-2-adamantanecarboxylic acid; Boc-Ada-OH; 2-((tert-Butoxycarbonyl)amino)tricyclo[3.3.1.13,7]decane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Aminoadamantane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.