Description

1-(3-Pyridinylcarbonyl)-4-Piperidinone(Saltdata: 1Hcl 0.22H2So4 0.1C3H8O) is a high-purity, advanced pharmaceutical intermediate with a defined salt composition. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and other therapeutic agents. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for neurological and psychiatric targets.
• API Synthesis: Used in the research and development (R&D) and scale-up production of new chemical entities (NCEs).
• Process Chemistry: Serves as a critical precursor in multi-step synthetic routes for GMP manufacturing.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial APIs.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and validation.

Basic Information

Product Name	1-(3-Pyridinylcarbonyl)-4-Piperidinone(Saltdata: 1Hcl 0.22H2So4 0.1C3H8O)
CAS No.	502925-00-0
Molecular Formula	C11H12N2O2 • xHCl • yH2SO4 • zC3H8O
Molecular Weight	Contact for details
Synonyms	4-Piperidinone, 1-(3-pyridinylcarbonyl)-, hydrochloride, sulfate, solvate; 1-(Pyridine-3-carbonyl)piperidin-4-one mixed salt; 3-(4-Oxopiperidine-1-carbonyl)pyridine salt; 502925-00-0; 1-(3-Pyridinecarbonyl)-4-piperidinone mixed salt; 1-(Nicotinoyl)-4-piperidinone salt mixture
EINECS	Contact for details

Quality Control

Our 1-(3-Pyridinylcarbonyl)-4-Piperidinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.