Description

Ethyl 3-Amino-3-[3-(Benzyloxy)Phenyl]Propanoate Oxalate is a high-purity, non-racemic chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex amines and amino acid derivatives for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and psychiatric drug candidates.
• Asymmetric Synthesis: Used as a starting material or intermediate in asymmetric catalytic reactions to construct complex molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Amino Acid Derivative Synthesis: Employed in the preparation of non-proteinogenic amino acids and their ester derivatives for peptide mimetics and other bioactive compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Process Chemistry: Investigated for scalable synthetic routes in the pilot-scale and commercial manufacturing of specialized fine chemicals.

Basic Information

Product Name	Ethyl 3-Amino-3-[3-(Benzyloxy)Phenyl]Propanoate Oxalate
CAS No.	502841-87-4
Molecular Formula	C20H23NO6
Molecular Weight	373.40 g/mol
Synonyms	Ethyl 3-Amino-3-(3-benzyloxyphenyl)propanoate oxalate; 3-Amino-3-(3-benzyloxyphenyl)propionic acid ethyl ester oxalate; (3R/S)-3-Amino-3-[3-(benzyloxy)phenyl]propanoic acid ethyl ester oxalate; Ethyl β-amino-β-(3-benzyloxyphenyl)propionate oxalate; 502841-87-4; Ethyl 3-amino-3-(3-(benzyloxy)phenyl)propanoate oxalic acid salt
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-3-[3-(Benzyloxy)Phenyl]Propanoate Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.