Description

6-Chloro-2-(Chloromethyl)Imidazo[1,2-A]Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct bicyclic heterocyclic structure. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) targeting complex therapeutic areas, offering a key building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel imidazopyridine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules for pharmacological evaluation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial APIs.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study specific biological pathways.

Basic Information

Product Name	6-Chloro-2-(Chloromethyl)Imidazo[1,2-A]Pyridine Hydrochloride
CAS No.	502841-53-4
Molecular Formula	C8H7Cl2N2•HCl
Molecular Weight	247.52 g/mol (Free base: 210.06 g/mol)
Synonyms	2-(Chloromethyl)-6-chloroimidazo[1,2-a]pyridine hydrochloride; 6-Chloro-2-(chloromethyl)imidazo[1,2-a]pyridine HCl; Imidazo[1,2-a]pyridine, 6-chloro-2-(chloromethyl)-, hydrochloride; 6-Chloro-2-chloromethylimidazo[1,2-a]pyridine hydrochloride; 502841-53-4; 6-Chloro-2-(chloromethyl)imidazo[1,2-a]pyridinium chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(Chloromethyl)Imidazo[1,2-A]Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and cGMP (current Good Manufacturing Practice) starting material applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.