Description

Methyl cis-3-Hydroxymethylcyclohexane-1-Carboxylate is a high-purity chiral building block and specialty intermediate of significant interest in advanced organic synthesis. Its value lies in the functionalized cyclohexane scaffold, which provides a versatile platform for constructing complex molecules with defined stereochemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals requiring specific stereoisomers.
• Ligand and Catalyst Development: The hydroxyl and ester functional groups make it a useful starting material for creating chiral ligands and organocatalysts.
• Academic and Industrial R&D: Employed in methodological studies and process chemistry for constructing complex, stereodefined carbocyclic systems.
• Material Science Precursor: Potential intermediate in the synthesis of specialized polymers and liquid crystals where the cyclohexane ring contributes to structural rigidity.

Basic Information

Product Name	Methyl cis-3-Hydroxymethylcyclohexane-1-Carboxylate
CAS No.	502650-56-8
Molecular Formula	C10H18O3
Molecular Weight	186.25 g/mol
Synonyms	Methyl (1R,3S)-3-(hydroxymethyl)cyclohexane-1-carboxylate; cis-3-(Hydroxymethyl)cyclohexanecarboxylic acid methyl ester; (1R,3S)-3-(Hydroxymethyl)cyclohexanecarboxylic Acid Methyl Ester; Methyl 3-(hydroxymethyl)cyclohexanecarboxylate (cis-); Cyclohexanecarboxylic acid, 3-(hydroxymethyl)-, methyl ester, cis-; (cis)-Methyl 3-hydroxymethylcyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl cis-3-Hydroxymethylcyclohexane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.