Description

4-Bromo-2-Vinylpyridine is a versatile halogenated vinylpyridine derivative, serving as a crucial building block in advanced organic synthesis. Its reactive vinyl and bromo substituents make it an invaluable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for coupling reactions and polymer modifications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactivity for structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Serves as a building block for creating novel pyridine-based ligands used in transition metal catalysis.
• Polymer and Material Science: Monomer for the synthesis of functionalized polymers, including conductive polymers and materials with tailored surface properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-2-Vinylpyridine
CAS No.	502509-20-8
Molecular Formula	C7H6BrN
Molecular Weight	184.03 g/mol
Synonyms	2-Ethenyl-4-bromopyridine; 4-Bromo-2-ethenylpyridine; 2-Vinyl-4-bromopyridine; 4-Bromo-2-vinyl-pyridine; 4-Bromovinylpyridine; Pyridine, 4-bromo-2-ethenyl-; 4-Bromo-2-vinylpyridine (CAS 502509-20-8)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Vinylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.