Description

1-(5-Chloropyridin-2-Yl)-1,4-Diazepane is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries. The compound, identified by CAS number 502133-62-2, is supplied with stringent quality control to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chloropyridine and diazepane motifs.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	1-(5-Chloropyridin-2-Yl)-1,4-Diazepane
CAS No.	502133-62-2
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	1-(5-Chloro-2-pyridinyl)-1,4-diazepane; 1,4-Diazepane, 1-(5-chloro-2-pyridinyl)-; 5-Chloro-2-(1,4-diazepan-1-yl)pyridine; 2-(1,4-Diazepan-1-yl)-5-chloropyridine; 1-(5-Chloropyridin-2-yl)-1,4-diazepane; 1-(5-Chloro-2-pyridyl)-1,4-diazepane
EINECS	Contact for details

Quality Control

Our 1-(5-Chloropyridin-2-Yl)-1,4-Diazepane is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support development projects requiring compliance with ICH guidelines and current Good Manufacturing Practice (cGMP) principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.