Description

4-(3-Carboxy-Pyridin-2-Yl)-[1,4]Diazepane-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique diazepane-pyridine carboxylic acid ester structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the development of new chemical entities.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for the production of active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing specialized fine chemicals for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and novel heterocyclic compound development.

Basic Information

Product Name	4-(3-Carboxy-Pyridin-2-Yl)-[1,4]Diazepane-1-Carboxylic Acid tert-Butyl Ester
CAS No.	502133-49-5
Molecular Formula	C17H23N3O4
Molecular Weight	333.38 g/mol
Synonyms	tert-Butyl 4-(3-carboxypyridin-2-yl)-1,4-diazepane-1-carboxylate; 1,4-Diazepane-1-carboxylic acid, 4-(3-carboxy-2-pyridinyl)-, 1,1-dimethylethyl ester; 4-(3-Carboxy-2-pyridinyl)-1,4-diazepane-1-carboxylic acid tert-butyl ester; 2-(1-(tert-Butoxycarbonyl)-1,4-diazepan-4-yl)nicotinic acid; Boc-4-(3-carboxy-2-pyridyl)-1,4-diazepane; 502133-49-5
EINECS	Contact for details

Quality Control

Our production of 4-(3-Carboxy-Pyridin-2-Yl)-[1,4]Diazepane-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.