Description

1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylic Acid, Methyl Ester is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its rigid, fused bicyclic structure, which serves as a critical scaffold in modern medicinal chemistry for the development of novel therapeutics. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of kinase inhibitors and other targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced drug candidates, particularly in oncology and inflammatory disease research.
• Kinase Inhibitor Scaffold: Serves as the core structure for developing potent and selective kinase inhibitors due to its ability to mimic ATP-binding motifs.
• Chemical Biology Probes: Used in the design and construction of molecular probes for studying enzyme function and cellular signaling pathways.
• Agrochemical Research: Employed as a building block in the discovery of new active ingredients for crop protection.
• Material Science: Potential monomer or precursor for creating specialized polymers with unique electronic or optical properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylic Acid, Methyl Ester
CAS No.	501892-49-5
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	Methyl 1H-pyrrolo[2,3-c]pyridine-2-carboxylate; 1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid methyl ester; Methyl 7-azaindole-2-carboxylate; 7-Azaindole-2-carboxylic acid methyl ester; 2-Carbomethoxy-7-azaindole; 1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid, methyl ester; 501892-49-5; Methyl 1H-pyrrolo[2,3-c]pyridin-2-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylic Acid, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.