Description

tert-Butyl 4-(3-Methoxyphenylamino)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with a protected amine and a methoxyaniline moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Integral in multi-step synthetic routes for producing potential active pharmaceutical ingredients with piperidine-based structures.
• Chemical Biology Probes: Serves as a starting material for creating specialized probes used to study biological pathways and protein interactions.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of bespoke organic compounds for client R&D.

Basic Information

Product Name	tert-Butyl 4-(3-Methoxyphenylamino)Piperidine-1-Carboxylate
CAS No.	501673-68-3
Molecular Formula	C17H26N2O3
Molecular Weight	306.40 g/mol
Synonyms	1-Boc-4-(3-methoxyanilino)piperidine; 1-(tert-Butoxycarbonyl)-4-[(3-methoxyphenyl)amino]piperidine; 4-(3-Methoxyanilino)-1-piperidinecarboxylic acid tert-butyl ester; tert-Butyl 4-[(3-methoxyphenyl)amino]-1-piperidinecarboxylate; N-(3-Methoxyphenyl)-4-piperidinamine, 1-Boc protected; 501673-68-3; 1-Boc-4-(3-methoxy-phenylamino)-piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Methoxyphenylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.