Description

Benzamide, 3,4,5-Trifluoro-n-4-Pyridinyl- (9Ci) is a high-purity, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring a trifluorinated benzamide moiety linked to a pyridine ring, makes it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, central nervous system (CNS), and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated aromatic compounds.

Basic Information

Item	Detail
Product Name	Benzamide, 3,4,5-Trifluoro-n-4-Pyridinyl- (9Ci)
CAS No.	501442-63-3
Molecular Formula	C12H6F3N2O
Molecular Weight	251.19 g/mol
Synonyms	3,4,5-Trifluoro-N-(pyridin-4-yl)benzamide; 4-Pyridinyl-3,4,5-trifluorobenzamide; N-(4-Pyridinyl)-3,4,5-trifluorobenzamide; 3,4,5-Trifluorobenzoic acid 4-pyridylamide; 3,4,5-Trifluoro-N-(4-pyridyl)benzamide; Benzamide, N-(4-pyridinyl)-3,4,5-trifluoro-
EINECS	Contact for details

Quality Control

Our Benzamide, 3,4,5-Trifluoro-n-4-Pyridinyl- (9Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.