Description

6-(1H-Pyrazol-1-Yl)Pyridine-2-Carbonitrile is a high-purity heterocyclic building block featuring a pyridine core functionalized with both a nitrile and a pyrazole group. This compound is of significant value in pharmaceutical and agrochemical research as a versatile intermediate for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.
• Agrochemical Research: Used in the synthesis of new generation herbicides and fungicides, leveraging its heterocyclic scaffold.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and coordination chemistry.
• Material Science: Employed in the research and development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and proteomics research.

Basic Information

Item	Detail
Product Name	6-(1H-Pyrazol-1-Yl)Pyridine-2-Carbonitrile
CAS No.	501378-98-9
Molecular Formula	C9H6N4
Molecular Weight	170.17 g/mol
Synonyms	6-(1H-Pyrazol-1-yl)pyridine-2-carbonitrile; 6-(1H-Pyrazol-1-yl)-2-pyridinecarbonitrile; 2-Cyano-6-(1-pyrazolyl)pyridine; 6-(Pyrazol-1-yl)picolinonitrile; 1-(6-Cyanopyridin-2-yl)-1H-pyrazole; Pyridine, 6-(1H-pyrazol-1-yl)-2-cyano-; 501378-98-9
EINECS	Contact for details

Quality Control

Our 6-(1H-Pyrazol-1-Yl)Pyridine-2-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.