Description

8-Chloro[1,2,4]Triazolo[4,3-A]Pyridine is a high-value nitrogen-containing heterocyclic compound that serves as a critical synthetic intermediate. Its fused triazolopyridine structure makes it a versatile building block for the development of novel active pharmaceutical ingredients and advanced materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Building block for creating organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Biology: Useful probe or fragment in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new heterocyclic chemistry.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of bespoke, high-value specialty chemicals.

Basic Information

Item	Details
Product Name	8-Chloro[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	501357-89-7
Molecular Formula	C6H3ClN4
Molecular Weight	166.57 g/mol
Synonyms	8-Chloro-1,2,4-triazolo[4,3-a]pyridine; 8-Chloro-[1,2,4]triazolo[4,3-a]pyridine; 8-Chloro-1H-[1,2,4]triazolo[4,3-a]pyridine; 8-Chlorotriazolopyridine; 8-Cl-Triazolopyridine
EINECS	Contact for details

Quality Control

Our 8-Chloro[1,2,4]Triazolo[4,3-A]Pyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.