Description

1-Oxa-8-Thia-3-Azaspiro[4.5]Decane-2,4-Dione(9Ci) is a high-purity, specialized heterocyclic compound featuring a unique spirocyclic structure containing oxygen, sulfur, and nitrogen atoms. This molecular architecture makes it a valuable and versatile building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging its spirocyclic scaffold for bioactivity.
• Material Science Research: Serves as a building block for developing advanced polymers, ligands for catalysis, or organic electronic materials due to its rigid, multi-heteroatom structure.
• Chemical Biology & Proteomics: Potential use as a specialized scaffold or linker in the design of chemical probes, enzyme inhibitors, or bioconjugation reagents.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: A critical starting material for custom manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	1-Oxa-8-Thia-3-Azaspiro[4.5]Decane-2,4-Dione(9Ci)
CAS No.	501127-74-8
Molecular Formula	C7H9NO3S
Molecular Weight	187.22 g/mol
Synonyms	1-Oxa-8-thia-3-azaspiro[4.5]decane-2,4-dione; 8-Thia-1-oxa-3-azaspiro[4.5]decane-2,4-dione; Spiro[1,4]oxathiane-2,4-dione derivative; 3-Azaspiro[4.5]decane-2,4-dione, 1-oxa-8-thia-; 501127-74-8; 1-Oxa-8-thia-3-azaspiro[4.5]decane-2,4-dione (9CI)
EINECS	Contact for details

Quality Control

Our 1-Oxa-8-Thia-3-Azaspiro[4.5]Decane-2,4-Dione(9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.