Description

1,4-Cyclohexadiene-1-Carboxylic Acid, 2-Amino-5-Hydroxy-3,6-Dioxo-, Ethyl Ester (9Ci) is a specialized, high-purity chemical intermediate with a complex bicyclic structure, offering unique reactivity for advanced synthesis. Its molecular architecture, featuring amino, hydroxyl, and multiple carbonyl functionalities, makes it a valuable building block for constructing complex heterocycles and pharmacologically active scaffolds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to innovate new active ingredients and functional molecules. CAS number 500867-24-3.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting complex disease pathways.
• Agrochemical Research: Used in developing new active ingredients for crop protection with potential novel modes of action.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex, polyfunctionalized organic molecules and heterocyclic compounds.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and functional pigments due to its conjugated system.
• Coordination Chemistry Ligand: Potential use as a chelating agent or ligand precursor in metal-organic frameworks (MOFs) and catalysis.
• Bioconjugation Chemistry: Its reactive functional groups make it suitable for developing linkers in bioconjugation and probe synthesis.

Basic Information

Product Name	1,4-Cyclohexadiene-1-Carboxylic Acid, 2-Amino-5-Hydroxy-3,6-Dioxo-, Ethyl Ester (9Ci)
CAS No.	500867-24-3
Molecular Formula	C9H11NO6
Molecular Weight	229.19 g/mol
Synonyms	Ethyl 2-amino-5-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-carboxylate; 2-Amino-5-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-carboxylic acid ethyl ester; 1,4-Cyclohexadiene-1-carboxylic acid, 2-amino-5-hydroxy-3,6-dioxo-, ethyl ester; Ethyl 2-amino-5-hydroxy-3,6-dioxocyclohexa-1,4-diene-1-carboxylate; 9CI Index Name Synonym; CAS 500867-24-3
EINECS	Contact for details

Quality Control

Our production of 1,4-Cyclohexadiene-1-Carboxylic Acid, 2-Amino-5-Hydroxy-3,6-Dioxo-, Ethyl Ester (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality system is designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.