Description

4-Pyridineaceticacid,α-Amino-α-Methyl-(9Ci) is a specialized pyridine derivative building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, including the α-amino-α-methyl substitution on the pyridineacetic acid backbone, which provides a versatile chiral center for constructing complex molecules. Pharmaceutical and agrochemical research and development teams need it as a critical intermediate for creating novel active ingredients, particularly in the development of targeted therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its pyridine core contributes to biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Research: The amino acid-like structure makes it valuable for designing and synthesizing peptide analogs and enzyme inhibitors.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein functions.
• Material Science: Potential use as a monomer or functional additive in the synthesis of specialty polymers with specific electronic or coordination properties.

Basic Information

Product Name	4-Pyridineaceticacid,α-Amino-α-Methyl-(9Ci)
CAS No.	500755-88-4
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	2-Amino-2-(4-pyridyl)propanoic acid; α-Amino-α-methyl-4-pyridineacetic acid; 2-Amino-2-methyl-2-(pyridin-4-yl)acetic acid; (RS)-2-Amino-2-(pyridin-4-yl)propanoic acid; 4-Pyridineacetic acid, α-amino-α-methyl-; DL-2-Amino-2-(4-pyridyl)propionic acid; 2-(4-Pyridyl)-2-aminopropanoic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity, purity, and consistency. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing specific batch results are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.