Description

5-Amino-2-Chloro-4-Methoxy-6-Methyl-Nicotinonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring reactive amino, chloro, and nitrile groups, makes it a versatile intermediate for constructing complex nitrogen-containing scaffolds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active nitrogen heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, library synthesis, and exploring new chemical transformations.
• Fine Chemical Production: Acts as a critical intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Amino-2-Chloro-4-Methoxy-6-Methyl-Nicotinonitrile
CAS No.	500341-70-8
Molecular Formula	C8H8ClN3O
Molecular Weight	197.62 g/mol
Synonyms	2-Chloro-4-methoxy-6-methyl-5-aminonicotinonitrile; 5-Amino-2-chloro-4-methoxy-6-methylpyridine-3-carbonitrile; 3-Cyano-5-amino-2-chloro-4-methoxy-6-methylpyridine; 2-Chloro-5-cyano-4-methoxy-6-methyl-3-pyridinamine; 500341-70-8; A2C4M6M Nicotinonitrile (abbrev.)
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloro-4-Methoxy-6-Methyl-Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.