Description

4-[(4-Bromophenyl)Methylideneamino]-5-Pyridin-4-Yl-2H-1,2,4-Triazole-3(4H)-Thione is a high-value heterocyclic organic compound featuring a fused triazole-thione core with bromophenyl and pyridinyl substituents. This molecular architecture makes it a critical advanced intermediate for pharmaceutical research and agrochemical development, where precise structural control is paramount. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Acts as a ligand or functional monomer in the creation of specialized polymers, metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its potential pharmacophore properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	4-[(4-Bromophenyl)Methylideneamino]-5-Pyridin-4-Yl-2H-1,2,4-Triazole-3(4H)-Thione
CAS No.	500278-32-0
Molecular Formula	C14H10BrN5S
Molecular Weight	360.23 g/mol
Synonyms	4-[(4-Bromobenzylidene)amino]-5-(pyridin-4-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 4-(4-Bromobenzylideneamino)-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol; 5-(4-Pyridinyl)-4-[[(4-bromophenyl)methylene]amino]-4H-1,2,4-triazole-3-thiol; 4-[(4-Bromophenyl)methyleneamino]-5-(4-pyridinyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 1,2,4-Triazole-3(4H)-thione, 4-[(4-bromophenyl)methyleneamino]-5-(4-pyridinyl)-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.