Description

Butanedioic Acid, 2-Iodo-3-Methyl-, 1-Ethyl 4-Methyl Ester, (2R,3R)-Rel- (9Ci) is a high-purity, stereochemically defined iodo-succinate derivative, serving as a critical chiral building block and advanced synthetic intermediate. Its value lies in the precise introduction of iodine and defined stereochemistry, enabling complex molecular construction in pharmaceutical and fine chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-fidelity intermediates for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting new therapeutic entities.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where specific spatial orientation is crucial for biological activity.
• Organic Synthesis Reagent: Acts as a versatile electrophilic iodination agent or a building block for constructing complex natural product analogs and specialty polymers.
• Chemical Biology Probe Development: Employed in the creation of molecular probes and labeled compounds for studying biochemical pathways and mechanisms.
• Material Science Research: Potential precursor for synthesizing functionalized organic materials with specific electronic or structural properties.

Basic Information

Product Name	Butanedioic Acid, 2-Iodo-3-Methyl-, 1-Ethyl 4-Methyl Ester, (2R,3R)-Rel- (9Ci)
CAS No.	500137-37-1
Molecular Formula	C8H13IO4
Molecular Weight	300.09 g/mol
Synonyms	(2R,3R)-2-Iodo-3-methylsuccinic Acid 1-Ethyl 4-Methyl Ester; rel-(2R,3R)-1-Ethyl 4-Methyl 2-Iodo-3-methylsuccinate; 1-Ethyl 4-methyl (2R,3R)-2-iodo-3-methylbutanedioate; 2-Iodo-3-methylsuccinic Acid Ethyl Methyl Ester, (2R,3R)-; Ethyl Methyl (2R,3R)-2-iodo-3-methylsuccinate; Iodomethylsuccinate Ethyl Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Butanedioic Acid, 2-Iodo-3-Methyl-, 1-Ethyl 4-Methyl Ester, (2R,3R)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for specified enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.