Description

5-Bromo-2-(3-Chloro-Pyridin-2-Yl)-3,4-Dihydro-2H-Pyrazole-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of agrochemicals and pharmaceuticals. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical manufacturing sectors for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development and production of next-generation pesticides and herbicides, leveraging its heterocyclic pyrazole-pyridine core.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex molecular architectures in medicinal chemistry and material science.
• R&D and Process Development: Serves as a standard or starting material in laboratory-scale research and scale-up process optimization for new chemical entities.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations engaged in the production of specialized fine chemicals and APIs.

Basic Information

Product Name	5-Bromo-2-(3-Chloro-Pyridin-2-Yl)-3,4-Dihydro-2H-Pyrazole-3-Carboxylic Acid Ethyl Ester
CAS No.	500011-91-6
Molecular Formula	C12H11BrClN3O2
Molecular Weight	344.59 g/mol
Synonyms	Ethyl 5-Bromo-2-(3-chloropyridin-2-yl)-3,4-dihydro-2H-pyrazole-3-carboxylate; 5-Bromo-2-(3-chloro-2-pyridinyl)-2,3-dihydro-3-pyrazolecarboxylic Acid Ethyl Ester; 2H-Pyrazole-3-carboxylic Acid, 5-Bromo-2-(3-Chloro-2-Pyridinyl)-3,4-Dihydro-, Ethyl Ester; 500011-91-6; 5-Bromo-2-(3-chloro-pyridin-2-yl)-2,3-dihydro-pyrazole-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(3-Chloro-Pyridin-2-Yl)-3,4-Dihydro-2H-Pyrazole-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and agrochemical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.