Description

4-[4-(4-Chlorophenyl)-4-Hydroxy-1-Piperidinyl]-1-(4-Chlorophenyl)-1-Butanone is a high-purity organic compound of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate, valued for its specific structural framework that enables the development of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted drug candidates.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for target molecules in pilot plant and commercial manufacturing.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Custom Synthesis: Starting material for the contract manufacturing of specialized fine chemicals and bespoke molecular entities.

Basic Information

Product Name	4-[4-(4-Chlorophenyl)-4-Hydroxy-1-Piperidinyl]-1-(4-Chlorophenyl)-1-Butanone
CAS No.	59995-68-5
Molecular Formula	C21H23Cl2NO2
Molecular Weight	392.32 g/mol
Synonyms	1-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-4-(4-chlorophenyl)-1-butanone; 4-(4-Chlorophenyl)-4-hydroxy-1-[4-(4-chlorophenyl)-4-oxobutyl]piperidine; Haloperidol Metabolite II; Reduced Haloperidol; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-[4-(4-Chlorophenyl)-4-Hydroxy-1-Piperidinyl]-1-(4-Chlorophenyl)-1-Butanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D and intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.