Description

1H-Benzo[D]Imidazole-2-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in organic chemistry. Its core value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl group into target molecules, which is critical for modifying physicochemical properties and biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs), dyes, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing sulfonamide-based drugs, including protease inhibitors, kinase inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides where the sulfonyl moiety enhances efficacy and selectivity.
• Dye and Pigment Manufacturing: Serves as a precursor for creating sulfonated dyes and pigments, improving solubility and color fastness.
• Polymer Chemistry: Employed in the modification of polymers and resins to introduce sulfonyl groups, altering thermal stability and chemical resistance.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.
• Ligand and Catalyst Design: Used to synthesize specialized ligands and organocatalysts for asymmetric synthesis and metal complexation.

Basic Information

Product Name	1H-Benzo[D]Imidazole-2-Sulfonyl Chloride
CAS No.	59940-07-7
Molecular Formula	C7H5ClN2O2S
Molecular Weight	216.64 g/mol
Synonyms	1H-Benzimidazole-2-sulfonyl chloride; 2-Benzimidazolesulfonyl chloride; Benzimidazole-2-sulfonyl chloride; 2-(Chlorosulfonyl)-1H-benzimidazole; 1H-1,3-Benzodiazole-2-sulfonyl chloride; 2-Sulfonylchloride benzimidazole; NSC 403079
EINECS	Contact for details

Quality Control

Our 1H-Benzo[D]Imidazole-2-Sulfonyl Chloride is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your specifications. Our quality systems are designed to support cGMP and ISO standards for critical pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.