Description

2-Chloro-5-Iodo-3-Methylpyridine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique substitution pattern makes it a valuable intermediate for researchers and manufacturers engaged in creating active ingredients, functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a building block for creating functionalized ligands, organic semiconductors, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Negishi) to construct complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
• Ligand Synthesis: Useful for the preparation of specialized nitrogen-containing ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Chloro-5-Iodo-3-Methylpyridine
CAS No.	59782-89-7
Molecular Formula	C6H5ClIN
Molecular Weight	253.47 g/mol
Synonyms	3-Methyl-2-chloro-5-iodopyridine; 5-Iodo-2-chloro-3-methylpyridine; 2-Chloro-3-methyl-5-iodopyridine; Pyridine, 2-chloro-5-iodo-3-methyl-; 2-Chloro-5-iodo-3-picoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodo-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.