Description

6-Chloro-5-Iodonicotinic Acid is a high-purity halogenated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it an invaluable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine scaffolds.

Basic Information

Product Name	6-Chloro-5-Iodonicotinic Acid
CAS No.	59782-87-5
Molecular Formula	C6H3ClINO2
Molecular Weight	283.45 g/mol
Synonyms	5-Iodo-6-chloropyridine-3-carboxylic acid; 3-Carboxy-5-iodo-6-chloropyridine; 6-Chloro-5-iodo-3-pyridinecarboxylic acid; 6-Chloro-5-iodonicotinic acid; 6-Chloro-5-iodo-nicotinic acid; 5-Iodo-6-chloronicotinic acid; 6-Chloro-5-iodo-pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Iodonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.