Description

4-Chloro-1,8-Naphthyridin-2(1H)-One is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized naphthyridine scaffold, which serves as a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antimicrobial programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic core.
• Material Science Research: Serves as a precursor for developing organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty dyes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Chloro-1,8-Naphthyridin-2(1H)-One
CAS No.	59514-93-1
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	4-Chloro-1,8-naphthyridin-2(1H)-one; 4-Chloro-1H-1,8-naphthyridin-2-one; 4-Chloro-2-hydroxy-1,8-naphthyridine; 2-Hydroxy-4-chloro-1,8-naphthyridine; 4-Chloro-2(1H)-oxo-1,8-naphthyridine; 59514-93-1; 4-Chloro-1,8-naphthyridin-2-ol
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-1,8-Naphthyridin-2(1H)-One is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.