Description

Ethane, 1,1,1-Trifluoro-2-Isothiocyanato- is a specialized fluorinated isothiocyanate building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, combining a reactive isothiocyanate group with a stable trifluoromethyl moiety, enabling the efficient introduction of fluorine into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated heterocycles and bioactive molecules, particularly in drug discovery programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the trifluoromethyl group improves lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for novel fluorinated polymers, liquid crystals, and functional materials with unique surface properties.
• Chemical Biology Probes: Utilized to create isothiocyanate-based labeling reagents and affinity probes for studying protein interactions and enzyme activity.
• Cross-coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to construct complex fluorinated architectures.

Basic Information

Product Name	Ethane, 1,1,1-Trifluoro-2-Isothiocyanato-
CAS No.	59488-39-0
Molecular Formula	C3H2F3NS
Molecular Weight	141.12 g/mol
Synonyms	2-Isothiocyanato-1,1,1-trifluoroethane; 1,1,1-Trifluoro-2-isothiocyanatoethane; 2,2,2-Trifluoroethyl isothiocyanate; Trifluoroethyl isothiocyanate; TFETC; NSC 334365; 1,1,1-Trifluoroethyl isothiocyanate; 2,2,2-Trifluoroethanamine, 1-isothiocyanato-
EINECS	Contact for details

Quality Control

Our Ethane, 1,1,1-Trifluoro-2-Isothiocyanato- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to supply chain reliability and batch-to-batch consistency supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature and reactive isothiocyanate group, minimize exposure to air and moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.