Description

Midazolam is a potent, short-acting benzodiazepine derivative central to modern medical practice. Its primary value lies in its rapid onset and short duration of action, making it a critical agent for procedural sedation and anesthesia induction. This compound is essential for pharmaceutical manufacturers, research institutions, and compounding facilities developing injectable sedatives, pre-anesthetic medications, and controlled substance research standards. We supply high-purity Midazolam CAS NO 59467-64-0 to support the stringent demands of global pharmaceutical supply chains.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of injectable sedative and anesthetic formulations.
• Preoperative Sedation: Used in medication for anxiolysis and amnesia before surgical or diagnostic procedures.
• Conscious Sedation: Key agent for sedation during minor surgeries, endoscopies, and dental procedures.
• Induction of Anesthesia: Employed as an intravenous agent to initiate general anesthesia.
• Status Epilepticus Management: Used in emergency medical settings for the control of severe, continuous seizures.
• Research & Development: Reference standard in analytical laboratories for method development and quality control testing.
• Compounding Pharmacy: Sourced by specialized pharmacies for preparing tailored medication solutions.

Basic Information

Product Name	Midazolam
CAS No.	59467-64-0
Molecular Formula	C₁₈H₁₃ClFN₃
Molecular Weight	325.77 g/mol
Synonyms	8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine; Dormicum; Hypnovel; Versed; Midazolamum; Ro 21-3981/001; 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-
EINECS	261-793-9

Quality Control

Our Midazolam is manufactured and tested under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical development and manufacturing. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While we can supply material referenced to major pharmacopeial standards (USP, EP, BP), specifications are tailored to client requirements to ensure optimal performance in your specific application.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). The product is light-sensitive and should be handled under appropriate conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.