Description

5-Hydroxy-6-Nitropyridine-3-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant commercial and research interest. Its unique structure, featuring both a carboxylic acid and a nitro-substituted hydroxyl group, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging its nitropyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands used in homogeneous catalysis and metal complexation.
• Material Science Research: Employed in the development of organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors for biochemical and pharmacological studies.

Basic Information

Product Name	5-Hydroxy-6-Nitropyridine-3-Carboxylic Acid
CAS No.	59288-43-6
Molecular Formula	C6H4N2O5
Molecular Weight	184.11 g/mol
Synonyms	6-Nitro-5-hydroxynicotinic acid; 3-Carboxy-5-hydroxy-6-nitropyridine; 5-Hydroxy-6-nitro-3-pyridinecarboxylic acid; 5-Hydroxy-6-nitronicotinic acid; 6-Nitro-5-hydroxy-3-pyridinecarboxylic acid; 5-Hydroxy-6-nitropyridine-3-carboxylate; 59288-43-6 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-6-Nitropyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.