Description

5-(Benzyloxy)-2-(Hydroxymethyl)Pyridin-4-Ol is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a benzyl-protected phenol and a hydroxymethyl group, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands used in homogeneous catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis and Contract Manufacturing: A high-purity intermediate for cGMP and non-GMP custom synthesis projects.

Basic Information

Product Name	5-(Benzyloxy)-2-(Hydroxymethyl)Pyridin-4-Ol
CAS No.	59281-14-0
Molecular Formula	C13H13NO3
Molecular Weight	231.25 g/mol
Synonyms	4-Pyridinol, 5-(benzyloxy)-2-(hydroxymethyl)-; 2-(Hydroxymethyl)-5-(phenylmethoxy)-4-pyridinol; 5-Benzyloxy-2-hydroxymethylpyridin-4-ol; 4-Hydroxy-5-(benzyloxy)-2-pyridinemethanol; 59281-14-0; 5-O-Benzyl-2-hydroxymethyl-4-hydroxypyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 5-(Benzyloxy)-2-(Hydroxymethyl)Pyridin-4-Ol is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality system is designed to support both research and development, as well as scale-up activities under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.