Description

Diethyl(4-Nitrophenyl)Phosphonate is a high-purity organophosphorus compound widely used as a key synthetic intermediate. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the synthesis of biologically active compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators, leveraging its phosphonate functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating novel phosphonate-based ligands for metal catalysis and organocatalysts.
• Material Science Research: Employed in the development of flame retardants, plasticizers, and other functional additives for polymers.
• Chemical Biology Probes: Utilized to synthesize phosphonate analogs of natural phosphates for studying enzyme mechanisms and biological pathways.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions, such as the Hirao reaction, to form carbon-phosphorus bonds.

Basic Information

Product Name	Diethyl(4-Nitrophenyl)Phosphonate
CAS No.	59262-45-2
Molecular Formula	C10H14NO5P
Molecular Weight	259.20 g/mol
Synonyms	Diethyl p-Nitrophenylphosphonate; (4-Nitrophenyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-(4-Nitrophenyl)-, Diethyl Ester; Diethyl 4-Nitrophenylphosphonate; Diethyl (4-Nitrophenyl)phosphonate; 4-Nitrophenylphosphonic Acid Diethyl Ester; Diethyl P-Nitrophenyl Phosphonate
EINECS	Contact for details

Quality Control

Our Diethyl(4-Nitrophenyl)Phosphonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.