Description

tert-Butyl-4-Bromobenzoate is a high-purity organic building block and pharmaceutical intermediate, specifically a para-substituted benzoate ester. This compound is valued for its role as a versatile synthon in complex organic synthesis, where the tert-butyl ester group offers orthogonal protection for carboxylic acids. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used in cross-coupling reactions (e.g., Suzuki, Stille) and as a protected carboxylic acid precursor.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers.
• Agrochemical Synthesis: Intermediate in the development of certain herbicides and plant growth regulators.
• Academic & Industrial R&D: Essential for methodological studies and scale-up process development in fine chemistry.

Basic Information

Product Name	tert-Butyl-4-Bromobenzoate
CAS No.	59247-47-1
Molecular Formula	C11H13BrO2
Molecular Weight	257.12 g/mol
Synonyms	4-Bromobenzoic Acid tert-Butyl Ester; p-Bromobenzoic Acid tert-Butyl Ester; tert-Butyl p-Bromobenzoate; Benzoic acid, 4-bromo-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-bromobenzoate; 4-Bromo-benzoic acid tert-butyl ester; t-Butyl 4-bromobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl-4-Bromobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high standards in pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.