Description

(4R)-3,5β,6Bβ-Trimethyl-4,4Aα,5,5Aα,6,6Aα,6B,7-Octahydrocycloprop[2,3]Indeno[5,6-B]Furan-4α-Ol Acetate is a high-purity, complex organic intermediate with a defined stereochemistry that is critical for advanced synthesis. This compound matters for its role as a key chiral building block in the production of sophisticated active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and specialty chemical sectors seeking reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex polycyclic frameworks in academic and industrial research.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals where precise stereochemical control is paramount.
• Process Chemistry Development: Employed in route scouting and optimization for scalable API manufacturing processes.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(4R)-3,5β,6Bβ-Trimethyl-4,4Aα,5,5Aα,6,6Aα,6B,7-Octahydrocycloprop[2,3]Indeno[5,6-B]Furan-4α-Ol Acetate
CAS No.	59246-85-4
Molecular Formula	C18H24O3
Molecular Weight	288.38 g/mol
Synonyms	4α-Acetoxy-3,5β,6bβ-trimethyl-4,4aα,5,5aα,6,6aα,6b,7-octahydrocyclopropa[2,3]indeno[5,6-b]furan; (4R)-4α-Acetoxy-3,5β,6bβ-trimethyl-4,4aα,5,5aα,6,6aα,6b,7-octahydro-1H-cyclopropa[2,3]indeno[5,6-b]furan; 4α-Acetoxy-3,5β,6bβ-trimethyl-4,4aα,5,5aα,6,6aα,6b,7-octahydro-1H-cyclopropa[2,3]indeno[5,6-b]furan; Cycloprop[2,3]indeno[5,6-b]furan-4α-ol acetate derivative; 59246-85-4
EINECS	Contact for details

Quality Control

Our (4R)-3,5β,6Bβ-Trimethyl-4,4Aα,5,5Aα,6,6Aα,6B,7-Octahydrocycloprop[2,3]Indeno[5,6-B]Furan-4α-Ol Acetate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.