Description

cis-2,6-Piperidine Dicarboxylic Acid is a high-purity chiral building block and versatile synthetic intermediate. This compound is critical for the development of novel pharmaceuticals and fine chemicals due to its rigid, bicyclic-like structure derived from the piperidine scaffold. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to catalyst synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs and enzyme inhibitors.
• Ligand Synthesis: Used in the preparation of sophisticated chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Conformationally Restricted Analogs: Serves as a constrained diacid or diamino acid surrogate in peptide chemistry to enhance metabolic stability and receptor selectivity.
• Agrochemical Research: Employed as a building block for novel herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable compound for medicinal chemistry programs and material science research exploring new molecular entities.

Basic Information

Product Name	cis-2,6-Piperidine Dicarboxylic Acid
CAS No.	59234-40-1
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	(2R,6S)-2,6-Piperidinedicarboxylic Acid; (2S,6R)-2,6-Piperidinedicarboxylic Acid; cis-2,6-Dicarboxypiperidine; (2R,6S)-Hexahydroisophthalic Acid; (2S,6R)-Hexahydroisophthalic Acid; cis-Hexahydroisophthalic Acid; 2,6-Piperidinedicarboxylic Acid, cis-; L-2,6-Diaminopimelic Acid Stereoisomer (related structure)
EINECS	Contact for details

Quality Control

Our cis-2,6-Piperidine Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.