Description

Methyl 2-Chloro-3-Cyano-6-Methylisonicotinate is a high-value pyridine derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its reactive chloro and cyano functional groups.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized pyridine-based polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	Methyl 2-Chloro-3-Cyano-6-Methylisonicotinate
CAS No.	59225-10-4
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	Methyl 2-chloro-3-cyano-6-methylpyridine-4-carboxylate; 2-Chloro-3-cyano-6-methylisonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 2-chloro-3-cyano-6-methyl-, methyl ester; Methyl 2-chloro-3-cyano-6-picolinate; 6-Methyl-2-chloro-3-cyanopyridine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Chloro-3-Cyano-6-Methylisonicotinate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.