Description

[2R,5S,(-)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethyl-4'-Oxospiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid is a high-purity, complex spirocyclic compound of significant interest in advanced organic synthesis. This specialized intermediate is valued for its unique stereochemistry and functional groups, which enable the construction of intricate molecular architectures. It is primarily sought by research institutions and pharmaceutical developers for use in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of new therapeutic agents, particularly in complex molecule synthesis.
• Advanced Organic Synthesis: Used in stereoselective reactions to construct complex spirocyclic and polycyclic frameworks for novel materials and chemicals.
• Chemical Research & Development: Serves as a reference standard or starting material in academic and industrial R&D for exploring new synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals requiring specific stereochemical control.

Basic Information

Product Name	[2R,5S,(-)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethyl-4'-Oxospiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid
CAS No.	59219-63-5
Molecular Formula	C23H34O4
Molecular Weight	374.52 g/mol
Synonyms	(-)-2R,5S-Spiroketal Acid; 5β-Cholan-24-oic Acid, 3-oxo-7α,12α-dihydroxy-, (5β)-; 7α,12α-Dihydroxy-3-oxo-5β-cholan-24-oic Acid; 3-Oxo-7α,12α-dihydroxy-5β-cholan-24-oic Acid; Spiro[4.5]decane-7-carboxylic Acid derivative; 5β-Cholanic acid derivative, 3-oxo-7α,12α-dihydroxy-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [2R,5S,(-)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethyl-4'-Oxospiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and related substances are provided and available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.