Description

1,3,3-Trimethyl-3H-Spiro[Isobenzofuran-1,4-Piperidine] is a high-purity, complex heterocyclic compound featuring a unique spirocyclic architecture. This structural motif makes it a valuable and versatile advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily sought after by research institutions and fine chemical manufacturers engaged in drug discovery and development, particularly within the central nervous system (CNS) and therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Key Intermediate in Pharmaceutical R&D: Serves as a critical building block for synthesizing potential drug candidates with spirocyclic cores.
• Neurological & Psychiatric Drug Development: Used in research targeting receptors and pathways within the central nervous system.
• Preclinical & Discovery Chemistry: Employed in medicinal chemistry programs to explore new chemical entities and structure-activity relationships (SAR).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in related synthetic processes.

Basic Information

Product Name	1,3,3-Trimethyl-3H-Spiro[Isobenzofuran-1,4-Piperidine]
CAS No.	59043-56-0
Molecular Formula	C15H19NO
Molecular Weight	229.32 g/mol
Synonyms	1,3,3-Trimethylspiro[isobenzofuran-1(3H),4'-piperidine]; 3H-Spiro[isobenzofuran-1,4'-piperidine], 1,3,3-trimethyl-; Spiro[isobenzofuran-1(3H),4'-piperidine], 1,3,3-trimethyl-; 59043-56-0; Trimethylspiroisobenzofuranpiperidine
EINECS	Contact for details

Quality Control

Our 1,3,3-Trimethyl-3H-Spiro[Isobenzofuran-1,4-Piperidine] is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.