Description

8-(Methylsulfonyl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is a high-purity, specialized heterocyclic building block featuring a unique spirocyclic structure. This compound is valued for its role as a key synthetic intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its spirocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	8-(Methylsulfonyl)-1,4-Dioxa-8-Azaspiro[4.5]Decane
CAS No.	59039-18-8
Molecular Formula	C8H15NO4S
Molecular Weight	221.27 g/mol
Synonyms	8-(Methanesulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(methylsulfonyl)-; 8-Methanesulfonyl-1,4-dioxa-8-azaspiro[4.5]decane; 8-Methylsulfonyl-1,4-dioxa-8-azaspiro[4.5]decane; Spirocyclic sulfonamide building block
EINECS	Contact for details

Quality Control

Our 8-(Methylsulfonyl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP starting material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.