Description

2,4-Difluorophenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block. Its value lies in its ability to introduce the difluorophenyl moiety into larger molecular structures, a key step in creating compounds with enhanced biological activity and metabolic stability. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluorophenyl group confers specific activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes and polyurea coatings with unique chemical resistance.
• Chemical Research: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced electronic materials and organic light-emitting diode (OLED) components.

Basic Information

Product Name	2,4-Difluorophenyl Isocyanate
CAS No.	59025-55-7
Molecular Formula	C7H3F2NO
Molecular Weight	155.10 g/mol
Synonyms	2,4-Difluorophenyl isocyanate; 1,3-Difluoro-4-isocyanatobenzene; Isocyanic Acid, 2,4-Difluorophenyl Ester; 2,4-DFPI; 2,4-Difluorobenzene Isocyanate; 4-Isocyanato-1,3-difluorobenzene; 2,4-Difluoro-1-isocyanatobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.