Description

1'-Ethyl-7-Methylspiro[Indoline-3,4'-Piperidin]-2-One is a high-purity, complex heterocyclic compound featuring a unique spirocyclic architecture that combines indoline and piperidine pharmacophores. This molecular structure makes it a critical intermediate in advanced organic synthesis, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by pharmaceutical R&D teams, contract research organizations (CROs), and manufacturers of specialty chemicals for life science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, receptor modulators, and other therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, drug-like spirocyclic scaffold.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein interactions.
• Advanced Organic Synthesis: Employed in method development and as a challenging substrate for novel catalytic reactions and asymmetric synthesis.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and regulatory filing support in drug development pipelines.

Basic Information

Product Name	1'-Ethyl-7-Methylspiro[Indoline-3,4'-Piperidin]-2-One
CAS No.	59022-56-9
Molecular Formula	C15H20N2O
Molecular Weight	244.33 g/mol
Synonyms	7-Methyl-1'-ethylspiro[indoline-3,4'-piperidin]-2-one; Spiro[indoline-3,4'-piperidin]-2-one, 1'-ethyl-7-methyl-; 1'-Ethyl-7-methyl-2-oxospiro[indoline-3,4'-piperidine]; 59022-56-9; 1'-Ethyl-7-methylspiro[indoline-3,4'-piperidine]-2-one
EINECS	Contact for details

Quality Control

Our 1'-Ethyl-7-Methylspiro[Indoline-3,4'-Piperidin]-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.