Description

1'-Ethylspiro[Indoline-3,4'-Piperidin]-2-One is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, especially within the central nervous system (CNS) and oncology domains.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• API Development: Integral to the development and scale-up processes for new Active Pharmaceutical Ingredients, particularly those targeting neurological receptors.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	1'-Ethylspiro[Indoline-3,4'-Piperidin]-2-One
CAS No.	59022-55-8
Molecular Formula	C15H20N2O
Molecular Weight	244.34 g/mol
Synonyms	1'-Ethylspiro[indoline-3,4'-piperidin]-2-one; 1'-Ethyl-2-oxospiro[indoline-3,4'-piperidine]; Spiro[indoline-3,4'-piperidin]-2-one, 1'-ethyl-; 1'-Ethyl-1,3-dihydrospiro[indene-2,4'-piperidin]-2-one (related structure); 59022-55-8; 1'-Ethylspiro[indoline-3,4'-piperidine]-2-one; 1'-Ethyl-2-oxo-spiro(indoline-3,4'-piperidine)
EINECS	Contact for details

Quality Control

Our 1'-Ethylspiro[Indoline-3,4'-Piperidin]-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support development projects requiring compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.